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3 Amazing ways to Shape up in Less than 7 days!
Imagine you need to look great to get all the attention at the biggest party of the year. The cloak has already started ticking and you have got 7 days to fix yourself for the D-Day. If you can take out 15 to 30 minutes in the next few days, you...
Acne Scar Removal Surgery
Acne scar removal surgery is one way of treating the scars left behind from acne. Acne scar removal surgery can be done by your dermatologist. If you are considering acne scar removal surgery be sure to do some research. Before you have acne scar...
Lower Your Cholesterol
Heart disease is the number one killer in the Western world today. More than 40% of men will die from it. What is particularly disturbing is that strokes and heart attacks are becoming much more common in younger men. Witness the recent death of...
Make-up Removal 101
It is important for people of all ages to take care of their
skin. In the hectic modern lives we live, it is often too easy
to neglect one's health and wellbeing. The state of your skin
says a lot about the state of your overall health, and with...
Summer Skin Care
Just as winter weather makes us pay special attention to our skin, summer with its sun and heat has its requirements too. SPF. SPF and more SPF. I know you heard a lot about it - but talking about summer skin care, I just have to remind you ...
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Accutane Side Effects: Should Depression Be A Concern?
Medical professionals and acne-pestered adolescents have no doubts about the effectiveness of the severe acne drug isotretinoin. It’s the looming possibility of side effects such as depression and fetal damage that makes people uneasy when considering using this medication.
Accutane (isotretinoin) is one of Hoffman-LaRoche’s most popular and controversial pharmaceuticals. This week, a study published in the Archives of Dermatology vindicated isotretinoin from causing depression. In this report, Christina Y. Chia, MD, from Saint Louis University Health Sciences Center, St. Louis, and colleagues examined whether patients with moderate to severe acne treated with isotretinoin experienced an increase in depressive symptoms compared with patients treated with a topical antibiotic, topical retinoid, and an oral antibiotic.
Dr. Chia found that “The use of isotretinoin in the treatment of moderate-severe acne in adolescents did not increase depressive symptoms. On the contrary, our study shows that treatment of acne improves depressive symptoms”.
Five years earlier, in 2000, the isotretinoin-depression link still appeared misleading. That time, the Archives of Dermatology posted study, headed by Dr. Susan S. Jick, from the Boston University School of Medicine, which found no evidence that isotretinoin increases the risk for depression, suicide, or other psychiatric disorders.
Even though isotretinoin finds ample support among dermatologists and psychiatrists, a host of parents, politicians and medical professionals hail isotretinoin as a medical misfortune.
For instance, Dr. David J. Graham, the Associate Director for Science and Medicine in FDA’s Office of Drug Safety, recently warned that Accutane should be taken off the market. And while there are few studies with any negative observations about isotretinoin, Dr. Douglas Bremner’s research at of the Emory University School of Medicine has linked isotretinoin treatment with changes in brain function. At the conclusion of this study, published in the American Journal of Psychiatry, Dr. Bremner concurred with Dr. Graham’s view that isotretinoin proves too dangerous for human use.
Dr. Bremner explains that to invoke depression, isotretinoin must influence the brain. During the
investigation, brain function of the subjects was measured using positron emission tomography (PET) before and after four months of treatment with isotretinoin. Isotretinoin treatment was associated with decreased brain metabolism in the orbitofrontal cortex- the area of the brain known to mediate symptoms of depression. Yet, there were no differences in severity of depressive symptoms between the isotretinoin and antibiotic treatment groups before or after treatment.
The pessimistic effects of isotretinoin also caught the attention of Diane K. Wysowski PhD. Dr. Wysowski noted that in June 2000, isotretinoin ranked among the top 10 drugs linked to depression and suicide attempts in the FDA's Adverse Event Reporting System database. In 2001, Dr. Wysowski examined isotretinoin’s depression inducing potential and posted her findings in the Journal of the American Academy of Dermatology. Dr. Wysowski concluded that more studies of isotretinoin are needed.
She also advised patients and their parents to immediately report mood swings and symptoms that are suggestive of depression such as sadness, crying, loss of appetite, unusual fatigue, withdrawal, and inability to concentrate to their prescribing physician. These protective measures can avoid more serious side effects and permit appropriate treatment, including consideration of drug discontinuation and referral for psychiatric care.
While dissension among researchers still exists about whether or not isotretinoin causes depression, one idea most of them can agree on is that more research on the side effects of isotretinoin are desirable. If you are not in the mood for being an isotretinoin guinea pig, Geoffrey Redmond MD, author of The Good News about Women’s Hormones, suggests using hormone therapy and/or using Retin-A if isotretinoin seems too chancy for you.
About the Author
Health author and Stanford University graduate Naweko San-Joyz lovingly writes from her home in San Diego. Her works include “Acne Messages: Crack the code of your zits and say goodbye to acne” (ISBN: 0974912204) and the upcoming work “Skinny Fat Chicks, Why we’re still not getting this dieting thing” (ISBN: 0974912212) for release in June of 2005. For useful acne self-help articles visit http://www.Noixia.com
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| Acne.org |
| Information on acne, medications and treatment of scars. Includes a regimen for keeping skin clear. |
| www.acne.org |
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| AcneNet |
| Dermatologist-reviewed information about acne, which lets people know that today virtually every case of acne can be resolved. |
| www.skincarephysicians.com |
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| What is Acne? |
| Information about the different types of acne lesions and what causes acne to develop. |
| www.skincarephysicians.com |
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| Questions and Answers About Acne |
| Illustrated information on causes of acne skin lesions, and tips and information on common treatments, their side effects, and current research. |
| www.niams.nih.gov |
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| Acne Resource Center |
| Acne, Nutrition, Research on Acne and Important Tips for Getting Acne Free. |
| www.acne-resource.org |
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| Acne - Wikipedia, the free encyclopedia |
| Acne is a group of skin rashes that have different causes. Acne vulgaris - most commonly experienced around puberty, typically of the face and ... |
| en.wikipedia.org |
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| Acne vulgaris - Wikipedia, the free encyclopedia |
| Different types of Acne Vulgaris: A: Cystic acne on the face, B: ... The vernacular term bacne or backne is often used to indicate acne found specifically ... |
| en.wikipedia.org |
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| MedlinePlus: Acne |
| From the National Institutes of Health; Questions and Answers about Acne (National Institute of ... Select services and providers for Acne in your area. ... |
| www.nlm.nih.gov |
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| MedlinePlus Interactive Tutorials: Acne |
| Acne. Start Tutorial. Starts multimedia presentation with questions. Requires Flash Player. Download Flash. download button for flash player. ... |
| www.nlm.nih.gov |
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| Acne Treatment by AcneHelper.com |
| Resource for acne treatments and prevention. Learn tips and techniques to stop pimples, zits and blackheads for good. |
| www.acnehelper.com |
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| Acne |
| Acne Creative bring brands to life through advertising, design and product ... Commercials, music videos and other film formats are made by Acne Film. ... |
| www.acne.se |
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| Acne Jeans |
| About · Collection · Acne Studios · Contact · Press/Retailer · Work at Acne Jeans · Newsletter · Shop (EU). Copyright © Acne Jeans. |
| www.acnejeans.com |
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| Acne |
| If you're almost a teen, chances are pretty good that you have some acne. About 8 in 10 preteens and teens have acne, along with many adults. |
| www.kidshealth.org |
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| Acne - treatment and causes of pimples and blackheads |
| What are the causes of acne and which skin treatments are most effective - BUPA health information factsheet. |
| hcd2.bupa.co.uk |
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| Natural Acne Treatment Information |
| Acne and Diet · The Risks and Side Effects of Prescription Acne Medications ... This is a great jumping off point for natural acne treatments. ... |
| www.absoluteacneinfo.com |
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| ASG www.stopspots.org ! | Index Acne, Pimples, Blackheads, Zits ... |
| Information and support on acne, including top ten tips, beauty tips and problems. |
| www.stopspots.org |
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| Acne.net - Acne & Skin Treatment Resource |
| Introduction to several forms of acne and some available treatments, by a dermatologist and medical school professor. |
| www.acne.net |
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| Acne.com - Acne Treatment Information |
| Acne.com - Acne Treatment Information. Your source for Acne information on the web. Learn more about what causes acne and how you can fight acne. |
| www.acne.com |
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| Acne – Complete medical information regarding acne and its ... |
| Complete medical explanation produced by doctors regarding acne, its causes, myths of causes, treatment on your own, and treatment by doctors. |
| www.medicinenet.com |
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| AAD - Acne |
| Acne is a skin condition which has plugged pores (blackheads and whiteheads), inflamed pimples (pustules), and deeper lumps (nodules). |
| www.aad.org |
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