|
|
|
Amritdhara Cure For Abdominal Bloating
Stomach gas is an extremely universal problem which largely
results due to improper eating habits. Just as the problem is
extremely common, so has modern medicine derived novel ways to
keep the problems in check - antacids. How modern antacids...
Herbal Nutrition Supplements: The 5W's
Herbal nutrition supplements are everywhere these days. So should you be taking them? To help you decide for yourself, here are the whos, whats, whens, wheres and whys on herbal nutrition. Herbal Nutrition Supplements: What Are They? The National...
Incredible - Essential - CoQ10
Deficiencies in CoQ10 (also known as Coenzyme Q10) can cause or aggravate many conditions such as heart disease, diabetes and periodontal disease.
"After age 20, levels of Coenzyme Q10 in your body decline gradually.After 50, it plummets."...
The Business Traveler’s Diet Problem: Staying Fit When on the Run
Despite the fact that accurate nutrition information can be accessed by almost anyone with an Internet connection or a library card, the 21st century has picked up where the last one left off: one dominated by poor eating habits. The reason for...
You Can't Predict, You Can Prepare
When opportunity knocks, can you open the door? When misfortune strikes, can you make it through unscathed? When you are faced with risk, uncertainty, and the unpredictable, your ability to deal with it is directly tied to your ability to...
|
|
| |
|
|
|
|
|
|
Accutane Side Effects: Should Depression Be A Concern?
Medical professionals and acne-pestered adolescents have no doubts about the effectiveness of the severe acne drug isotretinoin. It’s the looming possibility of side effects such as depression and fetal damage that makes people uneasy when considering using this medication.
Accutane (isotretinoin) is one of Hoffman-LaRoche’s most popular and controversial pharmaceuticals. This week, a study published in the Archives of Dermatology vindicated isotretinoin from causing depression. In this report, Christina Y. Chia, MD, from Saint Louis University Health Sciences Center, St. Louis, and colleagues examined whether patients with moderate to severe acne treated with isotretinoin experienced an increase in depressive symptoms compared with patients treated with a topical antibiotic, topical retinoid, and an oral antibiotic.
Dr. Chia found that “The use of isotretinoin in the treatment of moderate-severe acne in adolescents did not increase depressive symptoms. On the contrary, our study shows that treatment of acne improves depressive symptoms”.
Five years earlier, in 2000, the isotretinoin-depression link still appeared misleading. That time, the Archives of Dermatology posted study, headed by Dr. Susan S. Jick, from the Boston University School of Medicine, which found no evidence that isotretinoin increases the risk for depression, suicide, or other psychiatric disorders.
Even though isotretinoin finds ample support among dermatologists and psychiatrists, a host of parents, politicians and medical professionals hail isotretinoin as a medical misfortune.
For instance, Dr. David J. Graham, the Associate Director for Science and Medicine in FDA’s Office of Drug Safety, recently warned that Accutane should be taken off the market. And while there are few studies with any negative observations about isotretinoin, Dr. Douglas Bremner’s research at of the Emory University School of Medicine has linked isotretinoin treatment with changes in brain function. At the conclusion of this study, published in the American Journal of Psychiatry, Dr. Bremner concurred with Dr. Graham’s view that isotretinoin proves too dangerous for human use.
Dr. Bremner explains that to invoke depression, isotretinoin must influence the brain. During the
investigation, brain function of the subjects was measured using positron emission tomography (PET) before and after four months of treatment with isotretinoin. Isotretinoin treatment was associated with decreased brain metabolism in the orbitofrontal cortex- the area of the brain known to mediate symptoms of depression. Yet, there were no differences in severity of depressive symptoms between the isotretinoin and antibiotic treatment groups before or after treatment.
The pessimistic effects of isotretinoin also caught the attention of Diane K. Wysowski PhD. Dr. Wysowski noted that in June 2000, isotretinoin ranked among the top 10 drugs linked to depression and suicide attempts in the FDA's Adverse Event Reporting System database. In 2001, Dr. Wysowski examined isotretinoin’s depression inducing potential and posted her findings in the Journal of the American Academy of Dermatology. Dr. Wysowski concluded that more studies of isotretinoin are needed.
She also advised patients and their parents to immediately report mood swings and symptoms that are suggestive of depression such as sadness, crying, loss of appetite, unusual fatigue, withdrawal, and inability to concentrate to their prescribing physician. These protective measures can avoid more serious side effects and permit appropriate treatment, including consideration of drug discontinuation and referral for psychiatric care.
While dissension among researchers still exists about whether or not isotretinoin causes depression, one idea most of them can agree on is that more research on the side effects of isotretinoin are desirable. If you are not in the mood for being an isotretinoin guinea pig, Geoffrey Redmond MD, author of The Good News about Women’s Hormones, suggests using hormone therapy and/or using Retin-A if isotretinoin seems too chancy for you.
About the Author
Health author and Stanford University graduate Naweko San-Joyz lovingly writes from her home in San Diego. Her works include “Acne Messages: Crack the code of your zits and say goodbye to acne” (ISBN: 0974912204) and the upcoming work “Skinny Fat Chicks, Why we’re still not getting this dieting thing” (ISBN: 0974912212) for release in June of 2005. For useful acne self-help articles visit http://www.Noixia.com
|
|
|
|
|
| National Library of Medicine - National Institutes of Health |
| Part of the National Institutes of Health, the National Library of Medicine offers access to health information for consumer, patient, and physicians ... |
| www.nlm.nih.gov |
|
| Health and Medical Information produced by doctors - MedicineNet.com |
| Doctor-produced health and medical information written for you to make informed decisions about your health concerns. |
| www.medicinenet.com |
|
| Medicine in the Yahoo! Directory |
| Collection of sites for health professionals, with sections on specific disciplines, organizations, continuing education, conferences, publications, ... |
| dir.yahoo.com |
|
| MedlinePlus Health Information from the National Library of Medicine |
| Health information from the National Library of Medicine. Easy access to Medline and Health topics, medical dictionaries, directories and publications. |
| medlineplus.gov |
|
| Medicine - Wikipedia, the free encyclopedia |
| Medicine is a branch of health science and the sector of public life ... The practice of medicine combines both science as the evidence base and art in the ... |
| en.wikipedia.org |
|
| Journal Home - Nature Medicine |
| Nature Medicine has a vacancy for a Locum Assistant Editor for six months. The position involves working in all aspects of the editorial process, ... |
| www.nature.com |
|
| The New England Journal of Medicine: Research & Review Articles on ... |
| The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial ... |
| content.nejm.org |
|
| eMedicine Clinical Knowledge Base |
| eMedicine features up-to-date, searchable, peer-reviewed medical journals, online physician reference textbooks, and a full-text article database in 62 ... |
| www.emedicine.com |
|
| Open Directory - Health: Medicine |
| the entire directory, only in Health/Medicine. Top: Health: Medicine (11429). Description · Medical Specialties (4888); Surgery (2265) ... |
| dmoz.org |
|
| the www virtual library biosciences medicine |
| www.ohsu.edu/cliniweb/wwwvl/ - Similar pages |
|
|
| Medicine - home |
| Bimonthly journal covering the latest results in clinical investigation relevant to hospital and office practice. |
| www.md-journal.com |
|
| Institute of Medicine |
| The Institute of Medicine serves as adviser to the nation to improve health. |
| www.iom.edu |
|
| ScienceDaily: Health & Medicine News |
| Medical Research News. Health news on everything from cancer to nutrition. Full-text, images, updated daily. |
| www.sciencedaily.com |
|
| Google Directory - Health > Medicine |
| Search only in Medicine Search the Web. Medicine. Health > Medicine, Go to Directory Home. Categories. Alternative Medicine (6308) Basic Sciences (66) ... |
| www.google.com |
|
| the world wide web virtual library biosciences medicine |
| www.mcb.harvard.edu/biopages/medicine.html - Similar pages |
|
|
| PLoS Medicine - A Peer-Reviewed Open-Access Journal |
| PLoS Medicine is a peer-reviewed, international, open-access journal published ... Every issue of PLoS Medicine contains a selection of readers' responses. ... |
| medicine.plosjournals.org |
|
| Medicine On-Line - Medicine Online -The International Medical Journal |
| Medicine Online - independent and peer reviewed journal published by Priory Medical Journals - priory.com. |
| www.priory.com |
|
| Entrez PubMed |
| PubMed is a service of the US National Library of Medicine that includes over 16 million citations from MEDLINE and other life science journals for ... |
| www.ncbi.nlm.nih.gov |
|
| Stanford University School of Medicine |
| Home Page of the Stanford University School of Medicine. |
| med.stanford.edu |
|
| Medicine OnLine |
| Meds.com offers medical information and education on cancer (lung cancer, colon cancer, breast cancer, leukemia) and HIV / AIDS for patients, ... |
| www.meds.com |
|
|