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All about smoking and how to quit
Why do we smoke? Why do we smoke, when we all know that it is not good for health? There are very many reasons to it but in this article we will ponder over the biggest reason in today’s times and that is to release STRESS. What is stress, can we...
BREAST CANCER
Breast cancer occurs when cells in the breast begin to grow out of control enabling them to invade nearby tissues or spread throughout the body. Collections of these out of control tissues are called tumors. However, not all breast tumors are...
Introduction to Aromatherapy
Copyright 2004 by http://www.organicgreens.us and Loring Windblad. This article may be freely copied and used on other web sites only if it is copied complete with all links and text intact and unchanged except for minor improvements such as...
The Many Benefits of Green Tea Extract
The Benefits of Green Tea Extract: Anti-Aging, Anti-Cancer, Weight Control One of the great advancements in nutrition in the twenty-first century is the scientific confirmation of the many benefits of green tea extract. Here are just a few....
We Are Not Immune: Women and Heart Attacks
Heart disease is the #1 killer of women in America. Approximately 1 in 3 women die each year due to heart attack or stroke. Nearly twice as many women die of heart disease or stroke, than they do of any form of cancer, including breast cancer....
 
Acne: Trouble Over the Counter - Benzoyl Peroxide Banned by European Union

There are many over the counter (OTC) preparations for treatment of acne. Sold as lotions, gels, creams, and cleansers, OTC products can be a precarious buy and consumers should be aware that chemicals applied to the skin can also be absorbed into the body. The potential adverse effects of chemical agents make natural skin care products seem more attractive.

This is especially true for skin conditions such as acne and rosacea as harsh chemicals may only worsen matters. Synthetic chemicals can induce unnecessary inflammation beyond the confines of the sebaceous glands resulting in acne scars. Additionally, some chemicals can even be absorbed into the skin and have varying levels of systemic toxicity.

Benzoyl peroxide, the first topical agent for acne vulgaris, remains the most widely used OTC acne treatment in the United States. It is inexpensive to manufacture and widely marketed. Benzoyl peroxide dissolves comedons and has bactericidal effect by oxidizing proteins of the offending microbe, P. acne (Leyden, 1997). Though it may be effective for mild acne, benzoyl peroxide is not free from adverse effects according to the European Commission.

The most common adverse effect is extreme dryness of skin. It can also causes irritation, stinging, burning and peeling of skin. A formulation containing 2.5% benzoyl peroxide was found to have less burning and peeling of skin as compared with 5% or 10% benzoyl peroxide (Mills et al. 1986). Allergic contact dermatitis was found in 1-2% patients using benzoyl peroxide (Ives, 1992). It can cause bleaching of hair and clothing.

Temporary skin discoloration may occur if benzoyl peroxide is used with sunscreen containing para-amino benzoic acid (PABA). Similarly concomitant use of benzoyl peroxide with tretinoin can lead to severe irritation of skin. Benzoyl peroxide should not be used in pregnancy as its safety during pregnancy is not documented. The safety in breast-feeding women and children is also not established.

In animal studies, it was has found to induce skin cancer after 1 year of use (Kraus et al. 1995). Long-term studies are needed to profile its adverse effect in humans. Benzoyl peroxide has been banned for use in cosmetics by the European Union. OTC Acne treatments that contain benzoyl peroxide are included in this ban throughout Europe. Acne preparations made of benzoyl peroxide may contain various other chemical ingredients. Glycolic acid is a photo sensitizer and may be toxic to gastrointestinal system, nervous system and kidneys. Triethanolamine can form carcinogenic nitrosamine compounds


on the skin or in the body after absorption. It may also elicit immune reaction in form of allergic dermatitis or asthmatic attacks. Diisopropanolamine may release carcinogenic nitrosamine compounds.

While, benzoyl peroxide can be used for short-term treatment of mild acne in the US, its long-term use has the potential to damage skin. On the whole, safer options that allow natural resolution of acne are recommended. Natural alternatives to benzoyl peroxide are calendula or tea tree oil (Bassett et al. 1990). Psidium guajava and Juglans regia leaf extracts were found to be beneficial in treating acne (Qadan et al. 2005). Granulysin peptides were also found to be effective against P. acne and may form an alternative therapy against acne in future (McInturff et al. 2005).

If acne are severe and not amenable to benzoyl peroxide treatment, one should consult a dermatologist for prescription drugs like topical retinoids (Tretinoin, Adapalene and Tazarotene), topical antibiotics (clindamycin, erythromycin), oral isotretinoin, oral antibiotics (doxycycline, minocycline).

References: 1. Leyden JJ (1997) Therapy for acne vulgaris. New England Journal of Medicine 336, 1156-62. 2. Ives TJ (1992) Benzoyl peroxide, Am Pharm NS32 (8), 33-8. 3. Kraus AL, Munro IC, Orr JC, Binder RL, LeBoeuf RA, Williams GM (1995) Benzoyl peroxide: an integrated human safety assessment for carcinogenicity, Regul Toxicol Pharmacol 21, 87-107. 4. Mills OH Jr, Kligman AM, Pochi P, Comite H (1986) Comparing 2.5%, 5%, and 10% benzoyl peroxide on inflammatory acne vulgaris, Int J Dermatol 25, 664-7. 5. Bassett IB, Pannowitz DL, Barnetson RS (1990) A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Aust, 153: 455-8. 6. Qadan F, Thewaini AJ, Ali DA, Afifi R, Elkhawad A, Matalka KZ (2005) The antimicrobial activities of Psidium guajava and Juglans regia leaf extracts to acne-developing organisms. Am J Chin Med 33,197-204. 7. McInturff JE, Wang SJ, Machleidt T, Lin TR, Oren A, Hertz CJ, Krutzik SR, Hart S, Zeh K, Anderson DH, Gallo RL, Modlin RL, Kim J (2005) Granulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes. J Invest Dermatol 125, 256-63.

About the author:

James Dalton is a freelance writer specializing in skin conditions including acne, rosacea, and eczema. Visit http://www.AcneResearchLabs.com for more information regarding natural skin care solutions including effective acne treatment and rosacea treatment for sensitive skin.

 

BreastCancer.org - Breast Cancer Treatment Information and Pictures
Breast Cancer Information from a Nonprofit Organization.
www.breastcancer.org
 
The Breast Cancer Site
Founded to help offer free mammograms to underprivileged women nationwide. With a simple, daily "click" visitors help provide mammograms to those in need.
www.thebreastcancersite.com
 
Susan G. Komen Breast Cancer Foundation
The Susan G. Komen Breast Cancer Foundation is dedicated to education and research on breast cancer causes, treatment and the search for a cure.
www.komen.org
 
Breast Cancer Information from National Breast Cancer Foundation Inc
Breast cancer information including early signs and symptoms of breast cancer, myths, early detection, breast cancer research and more from National Breast ...
www.nationalbreastcancer.org
 
BreastCancer.Net: http://www.breastcancer.net
A clearinghouse for the latest news and information on the prevention, detection and treatment of breast cancer.
www.breastcancer.net
 
Breast Cancer Treatment with Traditional Chinese Medicine
Educational resources on using Traditional Chinese Medicine to treat and prevent breast cancer.
www.breastcancer.com
 
Breast Cancer Care - Homepage
Breast Cancer Care is the UK's leading provider of information, practical assistance and emotional support for anyone affected by breast cancer or breast ...
www.breastcancercare.org.uk
 
Breakthrough Breast Cancer
Breakthrough Breast Cancer is the UKs leading charity committed to fighting breast cancer through research and education.
www.breakthrough.org.uk
 
MedlinePlus: Breast Cancer
Search MEDLINE/PubMed for recent research articles on Breast Cancer: • Breast Cancer ... Select services and providers for Breast Cancer in your area. ...
www.nlm.nih.gov
 
Breast Cancer Research |
Online and print journal covering topics of basic and clinical research relevant to breast cancer. Research articles are free to all users.
breast-cancer-research.com
 
National Breast Cancer Centre - Evidence based information for ...
The National Breast Cancer Centre of Australia providing information about breast cancer for consumers and health professionals.
www.nbcc.org.au
 
Canadian Breast Cancer Foundation: Run for the Cure: Select Language
Charitable organization which raises money to advance research, education, diagnosis and treatment.
www.cbcf.org
 
Breast cancer - Wikipedia, the free encyclopedia
That is why you will see breast cancer patients wearing braces, ... [5] Men can also develop breast cancer, but their risk is less than one in 1000 (see sex ...
en.wikipedia.org
 
End Breast Cancer from Care2.com and TBCF!
Help stop Breast Cancer by clicking daily - free! Supports efforts by The Breast Cancer Fund.
breastcancer.care2.com
 
National Breast Cancer Foundation
The ultimate goal of the National Breast Cancer Foundation (NBCF) is to raise enough money to fund a cure for breast cancer. As Australia’s leading national ...
www.nbcf.org.au
 
Y-ME National Breast Cancer Organization
Support and information about the condition from this non-profit entity. Headquartered in Chicago, Illinois.
www.y-me.org
 
Breast Cancer Home Page - National Cancer Institute
Information about breast cancer treatment, prevention, genetics, causes, screening, clinical trials, research and statistics from the National Cancer ...
www.cancer.gov
 
What You Need To Know About™ Breast Cancer - National Cancer Institute
Information about detection, symptoms, diagnosis, and treatment of breast cancer. NIH Publication No. 05-1556.
www.cancer.gov
 
Breast Cancer Campaign - Researching the cure
Breast Cancer Campaign is the only charity that specialises in funding independent breast cancer research throughout the UK.
www.breastcancercampaign.org
 
NBCC - NBCC - National Breast Cancer Coalition
The National Breast Cancer Coalition Fund is a grassroots organization dedicated to ending breast cancer through the power of action and advocacy.
www.natlbcc.org
 
 

 
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