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All Natural Pain Relief
Vioxx was a very popular prescription pain medication taken by an estimated 20 million people. In September 2004 however, it was pulled from the market because a study found that its use increased the risk of heart attack and stroke. On Friday...

How Correct Nutrition can Improve the Health of your Hair
It is normal to lose 50 to 100 hairs a day. Beyond this, hair loss can result from general nutrient deficiency. One of the problems with nutrition and hair however is that we can't programme nutrients to do what we want - and hair growth is...

How to Lose Weight Successfully
For overweight and obese persons, losing weight is very hard. There are a lot of weight loss programs being offered in gyms nowadays but still, it’s so tiresome to go on and on to the gym just for this reason. I myself have been very interested to...

Impotence
Impotence Impotence facts in men In medical terminology it can be defined as the inability to have an erection of the penis adequate for sexual intercourse also called erectile dysfunction which affects as many as 18 million men in the United...

Understanding Obesity - How to Successfully Reduce Weight
THE CAUSES OF EXCESSIVE WEIGHT If you eat more nutrients containing energy than you need for your daily activities, for the internal processes of your body, and for the burning process that maintains the body temperature, the excessive...

 
Prostate Cancer with Low PSA

One of the problems with screening tests for cancer is that there is an assumption that if you have a negative test, you don't have cancer. Many people just don't realise that you can have cancer with a negative screening test. For prostate cancer serum PSA levels of 4 μg/L or more are considered to show the possible presence of cancer. An analysis of men in a large randomised study shows that cancer is also found in men with lower levels.

Although the risk of finding a cancer on biopsy is directly related to PSA levels below 4 μg/L, there is no PSA value below which a man has no risk of prostate cancer. Moreover, this statement applies not just to any grade of prostate cancer, but even to high grade cancers where disease progression in the absence of


treatment is to be expected.

Its importance is that it is a harsh reminder of the failures as opposed to the benefits of screening. Older men with normal PSA values of 4 μg/L or below should still be on the lookout for warning signs, as 1 in 8 will have prostate cancer worth treating despite that normal result.
About the Author

A Certified Family Physician of the Philippine Academy of Family Physician and continue to complete the requirements for Continuing Medical Education in Family Practice. Also a member of the Philippine Medical Informatics Society, Philippine Occupational Health and Safety Inc., and Pangasinan Medical Society. Faculty Department of Physiology (Medicine) Lyseum- Northwestern University, Dagupan, Pangasinan, Faculty Medical Informatics Lyseu

 

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