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Busting Acne Myths Requires Individualized Treatment and More Research
If you have acne, you know the deal- everybody has a cream or suggestion to help you get clear skin. But how do you separate myth, medicine and folklore to find an acne treatment that works for you? That’s what researcher Parker Magin set out to do...

Generic or Name Brand: Do You Really Need a Statin Drug?
In June 2006, insurers and government agencies will have the opportunity to start using an inexpensive generic version of the cholesterol-lowering drug Zocor instead of the more pricey Lipitor. Pfizer, which makes Lipitor, plans to use...

Got Stress?
I know it’s a silly question. We all have stress. Its source can be positive or negative and it helps us to meet the challenges we face in life. If you balance stress with relaxation you can avoid a myriad of health problems from tension...

How to Benefit from The Mind-Body Connection
Dr. Bernie Siegel, author of "Love, Medicine and Miracles" was once a distraught surgeon who fretted over his inability to effectively serve his cancer patients. Dr. Siegel's recognition and growing understanding of the mind-body connection...

It's Allergy Season: Don't Let it Ruin Your Thanksgiving
Writing this from Dallas, Texas one of the ragweed hotspots of the nation, I'm particularly aware of "allergies" and the havoc they can cause. Here are some facts about allergies: More than 50 million Americans suffer from allergies....

 
Prostate Cancer with Low PSA

One of the problems with screening tests for cancer is that there is an assumption that if you have a negative test, you don't have cancer. Many people just don't realise that you can have cancer with a negative screening test. For prostate cancer serum PSA levels of 4 μg/L or more are considered to show the possible presence of cancer. An analysis of men in a large randomised study shows that cancer is also found in men with lower levels.

Although the risk of finding a cancer on biopsy is directly related to PSA levels below 4 μg/L, there is no PSA value below which a man has no risk of prostate cancer. Moreover, this statement applies not just to any grade of prostate cancer, but even to high grade cancers where disease progression in the absence of


treatment is to be expected.

Its importance is that it is a harsh reminder of the failures as opposed to the benefits of screening. Older men with normal PSA values of 4 μg/L or below should still be on the lookout for warning signs, as 1 in 8 will have prostate cancer worth treating despite that normal result.
About the Author

A Certified Family Physician of the Philippine Academy of Family Physician and continue to complete the requirements for Continuing Medical Education in Family Practice. Also a member of the Philippine Medical Informatics Society, Philippine Occupational Health and Safety Inc., and Pangasinan Medical Society. Faculty Department of Physiology (Medicine) Lyseum- Northwestern University, Dagupan, Pangasinan, Faculty Medical Informatics Lyseu

 

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